The Science of Positive Personal Affirmations

Dr. Robert F. Mullen

Dr. Mullen is doing impressive work helping the world. He is the
pioneer of proactive neuroplasticity utilizing DRNI—deliberate,
repetitive, neural information. WeVoice.

To appreciate the importance of positive personal affirmations, we must understand the science of proactive neuroplasticity and the deliberate, repetitive input of neural information or DRNI.


Neuroplasticity is the scientific evidence of our brain’s constant adaptation to information. Without plasticity, our human brain would be incapable of learning, our body incapable of sustaining life. Research has firmly established that our neural network is a dynamic organism, constantly modifying and rebuilding to every new input of information. It is how we embrace new experiences, learn new information, and create new memories.

Scientists refer to the process of neuroplasticity as structural remodeling of the brain.

What is exciting is that we can dramatically accelerate the brain’s adaptability to new learning by deliberately compelling it to reconfigure and repattern its neural circuitry, proactively transforming our thoughts, behaviors, and perspectives, creating healthy new mindsets, skills, and abilities.

The importance of DRNI or the deliberate, repetitive, neural information of positive personal affirmations cannot be overstated: DRNI facilitates our capacity to compel proactive neuroplasticity – to personally manipulate and control our emotional wellbeing and quality of life.

The Trajectory of Neural Information

Our neural pathways are not fixed but dynamic and malleable. Every input of information causes a receptor neuron to fire, transmitting electrical energy, neuron to neuron and throughout the nervous system. Information comes in the form of sight, noises, experience, phenomena, the prick of a needle. Anything and everything that impacts us whether consciously or unconsciously. This information impacts a receptor cell which relays it to a sensory neuron. At the same time, this information is algorithmically coded into positive or negative electrical energy. The sensory neuron fires the electrical energy to a terminal or post-synaptic cell which then forwards that information throughout the neural network. More relay neurons develop, and circuits realign and strengthen causing a cellular chain reaction that engages millions of participating neurons.

Three Forms of Neuroplasticity

Reactive neuroplasticity is our brain’s natural unconscious adaption to information. Sight, noises, phenomena, and so on. Active neuroplasticity happens through cognitive pursuits such as learning, engaging in social interactions, teaching, aerobics, and creating. Proactive neuroplasticity is the conscious and deliberate neural input of information. Proactive neuroplasticity is the most potent and effective means of neural restructuring because the calculated regimen of repetitive input compels our neural network to restructure. The deliberate repetition of positive personal affirmations is a very effective method of proactive neuroplasticity because the repeated input of positive information causes multiple receptor neurons to fire, dramatically accelerating and consolidating learning and unlearning. In the case of social anxiety disorder, it is the cognitive process of countering years of negative self-beliefs with positive or constructive information.

Proactive Neuroplasticity YouTube Series

We drastically underestimate the significance and effectiveness of PPAs because we don’t understand the science behind them. PPAs help us focus on goals, challenge negative, self-defeating beliefs, and reprogram our subconscious minds. PPAs are brief, individually focused statements that we repeat to ourselves to describe what and who we want to be.

PPAs should be rational, reasonable, possible, unconditional, problem-focused, brief, and first-person present time. Rational because our objective is to subvert the irrationality of our negative self-beliefs.

Rational: The objective is to challenge the negative self-beliefs and image generated by dysfunction and/or life experiences.

Reasonable: Sensible; of sound judgment. The PPA I will publish my first novel is an unreasonable expectation if we choose to remain illiterate.

Possible: If goals are impossible, efforts are counter-productive and futile. I will win a Grammy is probably not a viable option for the tone-deaf.

Problem or Goal-focused: the path to an unknown destination will be inconclusive and meandering.

Unconditional: Independent of self-imposed restrictions.

First-person, present time: The past is immutable; the future indeterminate but projectable.

Brief: Direct and easily memorized.

Think of PPAs as aspirations or self-fulfilling prophecies. Practicing positive personal affirmations is an extremely effective form of DRNI or the deliberate, repetitive input of neural information.

Neural Reciprocation

Our brain reciprocates our efforts in abundance because every viable input of information engages millions of neurons with their own energy transmission. 

Our brain is an organic reciprocator. It codes our information into negative or positive electrical energy. The energy of the information is reciprocated in abundance because a single neuron receptor will engage millions of neurons, each with its own energy transmissions, amplifying the energy on a massive scale. Multiple repetitions of positive information activate millions of neurons reciprocating positive energy in abundance. Positive energy in, positive energy reciprocated in abundance. 

Conversely, negative energy in, negative energy reciprocated in abundance. 


It is important to understand that our brain does not think; it provides the means for us to think along with certain intangibles like advanced consciousness. Our brain’s function is the maintenance of our heartbeat, nervous system, and blood flow. It tells us when to breathe, stimulates thirst, and controls our weight and digestion. 

Because our brain does not think, it is unable to distinguish healthy from toxic information, so the natural and constant neurotransmissions of pleasurable and motivational hormones happen whether we feed it self-destructive or constructive information.

That’s one of the reasons breaking a habit, keeping to a resolution, or achieving the desired goal is challenging and why positive informational input is crucial for recovery and self-transformation.

Of the nine hormones most impactful to our emotional wellbeing and quality of life, two have a direct bearing on our levels of stress and anxiety that interfere with recovery and our pursuit of goals and objectives.

Cortisol and adrenaline are fear and anxiety-provoking hormones. PPAs assist in decreasing their productivity. We can also alleviate the toxicity of these hormones through progressive muscle relaxation, controlled breathing, and other positive reinforcement approaches but PPAs are an effective means of alleviating the detrimental effects of cortisol and adrenaline.

The supportive hormones include GABA for relaxation, dopamine for pleasure and motivation, endorphins to elevate our mood, and serotonin for a sense of wellbeing. Acetylcholine supports our positivity, glutamate enhances our memory, and noradrenaline improves concentration. We want those rewards for positive information.

Theory posits that eleven repetitions of anything initiate the power of suggestion. Repeating a series of three PPAs 5 times, 3 times a day (which takes, roughly, two minutes) generates forty-five cellular chain reactions supporting the restructuring of our neural network.

Hebb’s Rule

Hebb’s rule states neurons that fire together, wire together. In other words, the more neurons communicate with one another, the stronger the connection (Hebbian Learning). The stronger the connection, the more neural reciprocation and hormonal support. Our neural circuits are like muscles. The more repetitions, the more flexible and powerful they become. PPAs – the conscious repetition of information correlates to more robust learning and unlearning.

Diligently repeating positive personal affirmations equates to the deliberate, repetitive, neural input of information (DRNI) essential to proactive neuroplasticity. Proactive neuroplasticity through DRNI is the most potent and effective means of learning and unlearning. It increases activity in the self-processing systems of the cortex, which counteracts years of negative neural input from our automatic negative thoughts and behaviors (ANTs).

An increase in learning efficacy arises from the repeated and persistent stimulation of PPAs. This activates long-term potentiation, which increases the strength of the nerve impulses along the connecting pathways, generating more energy. BDNF or brain-derived neurotrophic factors are proteins that neurons need for survival. The deliberate repetitive neural input of information generates higher levels of BDNF, which is associated with improved cognitive functioning, mental health, and memory.

Constructing Our PPAs

The strongest and most effective PPAs are calculated and specific to our intention. Are we challenging the core and intermediate negative beliefs that condition our behavior and negatively impact our self-esteem and motivation? Are we focused on a specific challenge? Are we embracing our character strengths, attributes, and virtues that support recovery and transformation? What is our end goal – the personal milestone we seek to achieve? Intention and content determine the integrity of information and its correlation to the durability and learning efficacy of the neural response.

Intention: How are we expediting our objective? What is our constructive plan of attack? If our goal is to become better educated, what are we going to study? What sources of information do we utilize? How are we going to challenge misinformation? If we are challenging our ANTs, which character strength do we emphasize, and which deficits do we challenge? What is our plan to utilize these strengths or deficits? 

Content: What are the actual words that construct our neural information—the statement that addresses the context and intention of our goal? What is the best mode of delivery that will cause the receptor neuron to spark and engage the full range of positive neural responses? 

Clarity on our intention expressed by correct content determines the integrity of information and its correlation to the durability and learning efficacy of the neural response.

Neural restructuring does not happen overnight. Recovery and achieving personal goals and objectives take persistence, perseverance, and patience. Recovery-remission from social anxiety is a year or more in recovery utilizing appropriate tools and techniques. Substance abuse programs recommend nurturing a plant or tropical fish during the first year before contemplating a personal relationship. However, once we begin the process of PPAs, progress is exponential.

Repeat your series of three PPAs 5 times.
Do this at least 3 times a day.
Modify monthly.

WHY IS YOUR SUPPORT SO IMPORTANT?  ReChanneling develops and implements programs to (1) moderate symptoms of emotional dysfunction and (2) pursue personal goals and objectives – harnessing our intrinsic aptitude for extraordinary living. Our paradigmatic approach targets the personality through empathy, collaboration, and program integration utilizing scientific and clinically practical methods including proactive neuroplasticity, cognitive-behavioral modification, positive psychology, and techniques designed to reinvigorate self-esteem. All donations support scholarships for groups, workshops, and practicums.

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